![](https://github.com/CogDisResLab/KRSA/raw/HEAD/man/figures/logo.png)
KRSA - KRSA: Kinome Random Sampling Analyzer
The goal of this package is to analyze the PamChip data and identify the changes in the active kinome. The package can preprocess the PamChip data output from BioNavigator and use Random Sampling and Permutation Analysis to identify upstream kinases. Additionally, this package provides a set of useful visualizations for the PamChip data.
Last updated 2 hours ago
kinasephosphatasespamchipkinomerandom samplingpermutation analysis
4 stars 1.16 score 60 dependenciesdrugfindR - Investigate iLINCS for candidate repurposable drugs
This package provides a convenient way to access the LINCS Signatures available in the iLINCS database. These signatures include Consensus Gene Knockdown Signatures, Gene Overexpression signatures and Chemical Perturbagen Signatures. It also provides a way to enter your own transcriptomic signatures and identify concordant and discordant signatures in the LINCS database.
Last updated 14 days ago
lincsilincsdrug repurposingdrug discoverytranscriptomicsgene expressiongene knockdowngene overexpressionchemical perturbagendrugfindrbioinformaticsbioinformatics-pipeline
7 stars 1.85 score 39 dependenciescreedenzymatic - creedenzymatic
Combine kinome results from KRSA and UKA and other tools A package for integrating upstream kinases analyses
Last updated 3 months ago
1 stars 0.82 score 67 dependenciesBioPathNet - BioPathNet: Three Pod Analysis System
This package aims to provide a simple interface to perform the Three Pod Analysis of RNASeq dataaset. In addition, this also provides utility functions to perform the individual components.
Last updated 1 years ago
bioinformaticsbioinformatics-pipelineilincstranscriptomics
2 stars 0.36 score 69 dependenciesKINNET - Kinase INteraction NETwork Generation
This package provides the functionality to process PamGene's PamChip Data Output and generate kinase interaction networks from that. This project uses a bayesian algorithm to generate bayesian networks for defining dependence relationships between peptide sequences in the PamChip data. It then uses a novel kinase assignment method to assign upstream kinases to each peptide which is then output as a graph.
Last updated 2 years ago
2 stars 0.36 score 41 dependencies